scSeqComm is a bioinformatics tool to analyze cellular communication from single cell RNA-seq (scRNA-seq) data. scSeqComm allows to identify and quantify the evidence of an ongoing communication between cells through ligand-receptor pairs (intercellular signaling) and signaling paths from receptors to target genes in the receiving cells (intracellular signaling), as well as functionally characterize the response of receiving cells to the incoming cellular communication.


If you use the software for your research, please refer to the original scSeqComm paper with the citation below.

Giacomo Baruzzo, Giulia Cesaro, Barbara Di Camillo, Identify, quantify and characterize cellular communication from single-cell RNA sequencing data with scSeqComm, Bioinformatics, Volume 38, Issue 7, 1 April 2022, Pages 1920–1929,


The last version of scSeqComm is available at