Participation in the Brain Innovation Days 2024 in Brussels

The 4th edition of the Brain Innovation Days, organised by the European Brain Council, will take place on 13-14 November 2024 in Brussels, Belgium, under the overarching theme “Navigating the Brain Across a Lifetime“.
This event aims to bring the wider brain ecosystem together to foster dialogue, exchange knowledge, accelerate investment in research & innovation, and facilitate business development.

The main theme will revolve around 5 subthemes:

🧠 Blossoming Brains: Early Brain Development
🏫 Building Brains: Schools and Workplaces
🏥 Timeless Brains: Nurturing Resilience, Embracing Change
⚙️ Holistic Brains: Strategies for Brain Health in a Dynamic Society
🚀 Advancements in Neurotechnology: Pioneering Innovations

The programme will include a wide array of session types, including plenary sessions, inspiring Brain Talks, Poster and Innovation Showcase, matchmaking and networking activities, the Brain Innovation Days Pitch Competition, breakout sessions, panels, and how-to sessions.

Our PI Prof. Barbara Di Camillo will take part in the “Harnessing AI for brain health: lab to market to society” panel, an event that marks the conclusion of the BRAINTEASER project, celebrating its advances in remote prediction, prevention, and care for people with multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS). Key sessions will cover the transition of BRAINTEASER’s technology (an app and wearables) from the lab to the market, and the potential impact on patient-centred care. There will also be a showcase of the project’s clinical app and insights on its application to other neurodegenerative diseases like Parkinson’s.

The Brain Innovation Days offer an exciting opportunity to engage with the latest innovations in brain health, and we are proud to see Prof. Di Camillo contribute to the discussion on AI’s role in advancing care from lab to market, reinforcing our commitment to impactful, patient-centred research.

Sharing Our Research at CIBB 2024 in Benevento

These days our group is attending the 19th conference on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB 2024) in Benevento, Italy.

We are proud to contribute to the event with the special session “Informatics research in bioinformatics: Contributions from the CINI-InfoLife network” co-organised and co-chaired by our researchers Giacomo Baruzzo and Mikele Milia, part of Young-InfoLife, and the following 5 oral presentations, most of them developed within the projects we are involved in (PNC/PNRR DARE initiative, H2020 BRAINTEASER project, Horizon Europe REDDIE project):

  • “Comprehensive benchmarking of network inference methods for 16S rDNA-Seq data”, Piero Mariotto, Matteo Baldan, Barbara Di Camillo, and Giacomo Baruzzo
  • Comparing Propensity Score-Based Methods in Estimating the Treatment Effects: A Simulation Study, Sara Poletto, Enrico Longato, Erica Tavazzi, and Martina Vettoretti
  • “Effect of Clinical History on Predictive Model Performance for Renal Complications of Diabetes”, Davide Dei Cas, Barbara Di Camillo, Gian Paolo Fadini, Giovanni Sparacino and Enrico Longato
  • Exploring the Impact of Environmental Pollutants on Multiple Sclerosis Progression, Elena Marinello, Erica Tavazzi, Enrico Longato, Pietro Bosoni, Arianna Dagliati, Mahin Vazifehdan, Riccardo Bellazzi, Isotta Trescato, Alessandro Guazzo, Martina Vettoretti, Eleonora Tavazzi, Lara Ahmad, Roberto Bergamaschi, Paola Cavalla, Umberto Manera, Adriano Chiò and Barbara Di Camillo
  • “Network-Based Cross-Entropy Approach for Continuous Genotype-Phenotype Association Analysis”, Mikele Milia, Giacomo Baruzzo, and Barbara Di Camillo

We extend our sincere thanks to the conference organisers for facilitating this event and for providing us with the opportunity to present our research.

Highlights from IEEE EMBC 2024

From July 15th to 19th, 2024, our group participated in the 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) held in Orlando, Florida.

Our group was represented in the Health Informatics track with a poster presentation titled “Characterization of Chronic Kidney Disease Progression in Patients with Diabetes via Group-Based Multi-Trajectory Modeling”, authored by Alessandro Guazzo, Enrico Longato, Gian Paolo Fadini, Giovanni Sparacino, Rema Padman, and Barbara Di Camillo.

Additionally, our Principal Investigator, Prof. Barbara Di Camillo, was an organizer and speaker for two impactful mini-symposia.
The first mini-symposium, “Trustworthy AI in Medicine: Implications for Data, Algorithms and Systems,” took place on Wednesday, July 17th. This session addressed the critical issue of trustworthiness in AI systems used in clinical settings. The discussion covered various aspects, from data collection and preprocessing to algorithm reliability and explainability, drawing on practical examples from international projects such as the 4CE consortium and the BRAINTEASER project.
The second mini-symposium, “Fostering Equity in Science, Technology and Innovation: Insights and Best Practices in Co-Creating Policy Recommendations,” was held on Friday, July 19th. This session focused on promoting equity in these disciplines through collaborative policy-making. Experts from diverse backgrounds shared their experiences and best practices. The symposium provided valuable insights into the co-creation process, highlighting the importance of inclusivity and diversity in shaping effective policies.

We extend our gratitude to the organizers for making our participation in EMBC 2024 a fruitful experience, marked by engaging discussions and potential collaborations.

Great moments at BITS 2024 conference in Trento

Our group has attended the 20th Annual Meeting of the Bioinformatics Italian Society (BITS 2024) in Trento. It was an incredibly successful event!
We are proud to have contributed to the event with 2 oral presentations from Gaia and Piero:

  • “Limitations of the co-occurrence-based approach in the inference of microbiota interaction networks” Piero Mariotto, Matteo Baldan, Barbara Di Camillo, Giacomo Baruzzo
  • “Interactive exploration of cell-cell communication results from single-cell RNA sequencing data through a webapp” Gaia Tussardi, Giulia Cesaro, Barbara Di Camillo, Giacomo Baruzzo

Also, Gaia co-chaired the “YOUNG BITS, RSG-Italy & CINI Young-InfoLife” Symposium, a supporting and stimulating forum for undergraduate, master, PhD students and early stage researchers to present their research and to connect with the wider Italian Bioinformatics Community.

Key Takeaways from Our Team’s Participation at the World Health Forum Veneto 2024

On 21-22 March 2024, our team had the pleasure of attending the Artificial Intelligence for Medicine conference, hosted within the World Health Forum Veneto in Padova.

Our PI Prof. Barbara Di Camillo delivered an insightful talk titled “Bringing AI into clinical practice: A deep dive into the BRAINTEASER project”, where she presented our work to bring responsible AI into clinical practice. On this occasion, Professor Di Camillo was also interviewed by the prestigious Corriere della Sera, as featured in the article below.

This event was also an opportunity to present some of our group’s latest work. Our senior researchers Erica Tavazzi and Enrico Longato presented a poster titled “Improving Discrimination Performance in Artificial Intelligence Models for Rare Diseases: Strategies for Dealing with Data Scarcity”, sharing insights into strategies for enhancing predictive model performance with limited data.

This event, designed to examine the current state and explore the future of medical sciences and technologies aimed at enhancing care and life quality, was a great opportunity to network and foster new collaborations.

Advancing ALS Research: Collaborative Efforts with Precision ALS

Recently we had the pleasure to start collaborating with Precision ALS, a research programme for Amyotrophic Lateral Sclerosis (ALS) research across Europe, which brings together ALS clinicians, data scientists, and industries to provide new insights into the understanding of this rare disease. 

This month, we attended a Precision ALS meeting in Basel, where clinical, scientific, and industry experts gathered to discuss the latest frontiers in the development and utilisation of predictive models for ALS. Together with our partners from the University of Torino, we presented our research work in the field and the new models and tools developed within the H2020 BRAINTEASER Project.

Building upon our collective knowledge of AI applied to ALS research, we aspire to bring our expertise and insights into the collaborative initiatives of Precision ALS, advancing the understanding and treatment of this multifaceted, complex disease.

✨ CIBB2023 Success: Advancing Computational Intelligence

The General Chairs and Local Committee want to express their heartfelt gratitude to all of you who contributed to this unforgettable and remarkable conference 🙏 From inspiring keynote lecture to innovative talk and networking opportunities, CIBB2023 has bring together brilliant researchers from Bioinformatics, Biostatistics, Systems and Synthetic Biology, and Medical Informatics 🖥️

We are proud to have contributed to the event with

  • Leveraging on somatic sample simulators for realistic data-driven generation of tumoral genomes“, Francesca Longhin, Enidia Hazizaj, Giacomo Baruzzo and Barbara Di Camillo
  • N2BPC: an algorithmic approach from Networks to Bacteria’s metabolite Production and Consumption“, Matteo Baldan, Giacomo Baruzzo and Barbara Di Camillo
  • Bactlife: A Dash GUI to simulate bacterial communities evolution“, Massimo Bellato, Marco Cappellato, Sara Rebecca, Andrea Calzavara, Alessandro Lucchiari, Niccolò Venturini Degli Esposti and Barbara Di Camillo
  • Differential cellular communication analysis from large-scale single-cell RNA sequencing data“, Giulia Cesaro, Giacomo Baruzzo and Barbara Di Camillo

Exciting moments at ISMB/ECCB2023 conference in Lyon

Our group has attended the 31st Annual Intelligent Systems For Molecular Biology (ISMB) and the 22nd Annual European Conference on Computational Biology (ECCB) conference. It was an incredibly successful event!

🚀 Our Tutorial was a triumph!

We are elated by the overwhelming response to our tutorial “How to make reproducible, portable and reusable bioinformatics software using software containerization“. The high demand showcased the significance of this topic in the software development landscape.

🎤 Sysbiobig on the Stage!

It was a privilege and an honor to present our work among esteemed professionals and researchers through 4 oral presentations and 8 poster contributions

  • Oral communication & Poster contribution “Modeling the tumor microenvironment with a hybrid Multi-Agent Spatio-Temporal model fed with sequencing data” (Mikele Milia, Giulia Cesaro, Giacomo Baruzzo, Piegiorgio Alotto, Noel Filipe da Cunha Carvalho de Miranda, Zlatko Trajanoski, Francesca Finotello, Barbara Di Camillo)
  • Oral communication “CClens: a cellular communication workflow for large-scale single-cell RNA sequencing data” (Giulia Cesaro, Giacomo Baruzzo, Barbara Di Camillo)
  • Oral communication & Poster contribution “scSeqComm: a statistical and network-based framework to infer inter- and intra-cellular communication from single-cell RNA sequencing data” (Giacomo Baruzzo, Giulia Cesaro, Barbara Di Camillo)
  • Oral communication & Poster contribution “Comprehensive benchmarking of differential abundance methods in microbiome data” (Marco Cappellato, Giacomo Baruzzo, Barbara Di Camillo)
  • Oral communication “Interactive and effective visualization framework for interpreting and exploring cellular communication data” (Giulia Cesaro, Giacomo Baruzzo, Barbara Di Camillo)
  • Poster contribution: “Bactlife – A Dash GUI to simulate bacterial communities’ evolution via agent-based modeling” (Massimo Bellato, Marco Cappellato, Sara Rebecca, Andrea Calzavara, Alessandro Lucchiari, Niccolò Venturini Degli Espositi, Barbara Di Camillo)
  • Poster contribution “Towards automatic ACMG evidence identification for variant interpretation” (Francesca Longhin, Alessandro Guazzo, Enrico Longato, Diego Boscarino, Dino Paladin, Nicola Ferro, Barbara Di Camillo)
  • Poster contribution “Comprehensive review of tumoral sample simulators: building a realistic gold standard for somatic variant calling validation” (Francesca Longhin, Enidia Hazizaj, Giacomo Baruzzo, Barbara Di Camillo)
  • Poster contribution “mopo16Sweb: A webapp for multi-objective optimization of 16S rRNA primers sequences on the cloud” (Mikele Milia, Nicola Ferro, Barbara Di Camillo, Giacomo Baruzzo)
  • Poster contribution: “Shedding light on cellular communication analysis: the present and the future” (Giulia Cesaro, James S. Nagai, Alice Chiodi, Vanessa Klöker, Nicolò Gnoato, Ettore Mosca, Ivan Costa, Enrica Calura, Barbara Di Camillo, Giacomo Baruzzo)

In two weeks we will attend the 19th Annual Meeting of the Bioinformatics Italian Society (BITS 2023) with 1 oral communication & 3 poster contributions

  • Oral communication: “CClens: effective and efficient differential cellular communication analysis of large-scale single-cell RNA sequencing data” (G. Cesaro, G. Baruzzo, B. Di Camillo)


  • Poster contribution: “Data-driven meta-simulation of realistic tumoral samples” (F. Longhin, E. Hazizaj, G. Baruzzo, B. Di Camillo)
  • Poster contribution: “mopo16Sweb: a cloud-based app for multi-objective optimization of bacterial 16S PCR primers” (M. Milia, N. Ferro, B. Di Camillo, G. Baruzzo)
  • Poster contribution: “From microbial ground truth network simulation to inference method benchmark” (M. Baldan, A. Rossato, M. Bellato, G. Baruzzo, B. Di Camillo)

For more details, check the conference website: https://bioinformatics.it/bits2023

Systems Biology and Bioinformatics Group
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